CD44 Polyclonal Antibody

CAT#: AST-M001

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Overview Specification

Target	CD44
Cell Type	Types 1 and 2 astrocytes
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA
Reactivity	Human, mouse, rat, bovine, sika deer
Conjugate	Unconjugated
Keywords	Types 1 and 2 astrocytes; Rabbit; IgG; WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA

Product Information	It targets CD44 in WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA applications and shows reactivity with human, mouse, rat samples.
Background Information	CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple forms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and extensive post-translational modifications.
Synonyms	CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
Full Name	CD44 molecule (Indian blood group)
Tested Reactivity	Human, mouse, rat
Cited Reactivity	Human, mouse, rat, Bovine, sika deer
Type	Antibody
Class	Polyclonal
Immunogen	CD44 fusion protein
Calculated Molecular Weight	742 aa, 82 kDa
Observed Molecular Weight	80-95 kDa
GenBank Accession Number	BC004372
Gene ID	960
Gene Symbol	CD44
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	MDA-MB-231 cells, HeLa cells, HUVEC cells, mouse thymus tissue, A549 cells
Positive IP Detected	HeLa cells
Positive IHC Detected	Human lung cancer tissue, human colon cancer tissue, human oesophagus cancer tissue
Positive IF Detected	HeLa cells, human colon cancer tissue
Positive FC Detected	HeLa cells

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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