GFAP Monoclonal Antibody

CAT#: AST-M002

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Overview Specification

Target	GFAP
Cell Type	Types 1 and 2 astrocytes
Host	Mouse
Isotype	IgG2a
Applications	WB, IP, IHC, IF, Dot blot, ELISA
Reactivity	Human, mouse, rat, pig, rabbit
Conjugate	Unconjugated
Keywords	Types 1 and 2 astrocytes; Mouse; IgG2a; WB, IP, IHC, IF, Dot blot, ELISA

Product Information	It targets GFAP in WB, IP, IHC, IF, Dot blot, ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Background Information	GFAP (Glial fibrillary acidic protein) is a type III intermediate filament (IF) protein specific to the central nervous system (CNS). GFAP is one of the main components of the intermediate filament network in astrocytes and has been proposed as playing a role in cell migration, cell motility, maintaining mechanical strength, and in mitosis. Tissue specificity GFAP is expressed in central nervous system cells, predominantly in astrocytes. GFAP is commonly used as an astrocyte marker. However, GFAP is also present in peripheral glia and in non-CNS cells, including fibroblasts, chondrocytes, lymphocytes, and liver stellate cells (PMID: 21219963).
Synonyms	GFAP, glial fibrillary acidic protein, Intermediate filament protein
Full Name	Glial fibrillary acidic protein
Tested Reactivity	Human, mouse, rat, pig, rabbit
Cited Reactivity	Human, mouse, rat, pig, rabbit
Type	Antibody
Class	Monoclonal
Immunogen	GFAP fusion protein
Calculated Molecular Weight	432 aa, 50 kDa
Observed Molecular Weight	45-52 kDa
GenBank Accession Number	BC013596
Gene ID	2670
Gene Symbol	GFAP
Form	Liquid
Purification Method	Protein A purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Rat brain tissue, human brain tissue, pig brain tissue, U-251 cells, rat cerebellum, mouse brain, mouse cerebellum, rabbit brain
Positive IP Detected	Mouse brain tissue
Positive IHC Detected	Human brain tissue, human gliomas tissue, mouse brain tissue, rat brain tissue
Positive IF Detected	Rat brain tissue

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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