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Human GAD1 / GAD67 Protein, His Tag

Human GAD1 / GAD67 Protein, His Tag

CAT#: IVD-P014

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Overview Specification
Species Human
Tag His
Expression Systems Baculovirus-Insect cells
Keywords In vitro diagnostic proteins
Synonyms GAD1, GAD67, Glutamate decarboxylase 1
Background Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA), the major inhibitory transmitter in higher brain regions, and putative paracrine hormone in pancreatic islets. GAD67 is cytoplasmic (594 a.a.), and seems to be responsible for significant cytoplasmic GABA production.
Source Human GAD1
SWISS Q99259-1
Theoretical Molecular Weight 68.8 kDa
Formulation Supplied as 0.2 μm filtered solution in 20 mM Tris, 500 mM Nacl, pH 8.5 with glycerol as protectant.
Molecular Characterization This protein carries a polyhistidine tag at the N-terminus. The protein migrates as 66 kDa, 90 kDa and >116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Less than 1.0 EU per μg by the LAL method.
Purity >85% as determined by SDS-PAGE.
Storage Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
Shipping This product is supplied and shipped with dry ice, please inquire the shipping cost.
Notes This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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