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Learn MoreCAT#: IVD-P016
Species | Human |
Tag | His |
Expression Systems | HEK293 cell |
Keywords | In vitro diagnostic proteins |
Synonyms | MOG, BTN6, BTNL11, MOGIG2, NRCLP7, Myelin oligodendrocyte glycoprotein |
Background | Myelin oligodendrocyte glycoprotein (MOG), is a single-pass transmembrane glycoprotein of the immunoglobulin (Ig) superfamily. MOG is a myelin protein exclusively expressed in the CNS at the outermost surface of myelin sheaths and oligodendrocyte membranes. This makes MOG a potential target of cellular and humoral immune responses in inflammatory demyelinating diseases. Due to its late postnatal developmental expression, MOG is an important marker for oligodendrocyte maturation. |
Source | Human MOG |
SWISS | Q16653-1 |
Theoretical Molecular Weight | 16.2 kDa |
Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant. |
Reconstitution | Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA. |
Molecular Characterization | This protein carries a polyhistidine tag at the C-terminus. The protein migrates as 20-24 kDa when calibrated against star ribbon prestained protein marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin | Less than 1.0 EU per μg by the LAL method. |
Purity | >90% as determined by SDS-PAGE. |
Storage | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Notes | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |