MSI1 Polyclonal Antibody
CAT#: AST-M004
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Overview
Specification
| Target
|
MSI1 |
| Cell Type
|
Type 2 astrocytes |
| Host
|
Rabbit |
| Isotype
|
IgG |
| Applications
|
WB, IHC, IF, ELISA |
| Reactivity
|
Human |
| Conjugate
|
Unconjugated |
| Keywords
|
Type 2 astrocytes; Rabbit; IgG; WB, IHC, IF, ELISA |
| Product Information
|
The immunogen of MSI1 Fusion Protein expressed in E. coli. |
| Background Information
|
Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary. |
| Synonyms
|
MSI1, Musashi 1, musashi homolog 1 (Drosophila) |
| Full Name
|
Musashi homolog 1 (Drosophila) |
| Tested Reactivity
|
Human |
| Cited Reactivity
|
Human |
| Type
|
Antibody |
| Class
|
Polyclonal |
| Immunogen
|
MSI1 fusion protein |
| Calculated Molecular Weight
|
362 aa, 39 kDa |
| Observed Molecular Weight
|
35 kDa |
| GenBank Accession Number
|
BC146463 |
| Gene ID
|
4440 |
| Gene Symbol
|
MSI1 |
| Form
|
Liquid |
| Purification Method
|
Antigen affinity purification |
| Storage Buffer
|
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions
|
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage. |
| Positive WB Detected
|
HEK-293 cells, Caco-2 cells, HEK-293T cells |
| Positive IHC Detected
|
Human gliomas tissue |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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