MSI1 Polyclonal Antibody

CAT#: AST-M004

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Overview Specification

Target	MSI1
Cell Type	Type 2 astrocytes
Host	Rabbit
Isotype	IgG
Applications	WB, IHC, IF, ELISA
Reactivity	Human
Conjugate	Unconjugated
Keywords	Type 2 astrocytes; Rabbit; IgG; WB, IHC, IF, ELISA

Product Information	The immunogen of MSI1 Fusion Protein expressed in E. coli.
Background Information	Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
Synonyms	MSI1, Musashi 1, musashi homolog 1 (Drosophila)
Full Name	Musashi homolog 1 (Drosophila)
Tested Reactivity	Human
Cited Reactivity	Human
Type	Antibody
Class	Polyclonal
Immunogen	MSI1 fusion protein
Calculated Molecular Weight	362 aa, 39 kDa
Observed Molecular Weight	35 kDa
GenBank Accession Number	BC146463
Gene ID	4440
Gene Symbol	MSI1
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	HEK-293 cells, Caco-2 cells, HEK-293T cells
Positive IHC Detected	Human gliomas tissue

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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