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Neurotransmitter Probe Neural Stem Cell Lines

Neurotransmitter Probe Neural Stem Cell Lines

Alfa Cytology has achieved the direct reprogramming of adult cells into NSCs or the differentiation of induced pluripotent stem cells (iPSCs) to obtain a large number of NSCs, which has enabled the transplantation of NSCs into clinical applications.

Introduction to Neurotransmitter Probe Neural Stem Cell Lines

Complex brain functions cannot be realized without efficient and specific information exchange and integration between neurons, and neurotransmitters, as important small biological molecules are involved in the chemical synapse-mediated information transfer process between neurons. Traditional direct measurements do not allow for the detection of transmitters at the level of individual cells and have insufficient specificity and poor temporal and spatial accuracy.

The novel probe GRAB (GPCR activation-based sensor) can accurately detect neurotransmitter dynamics in real time with high sensitivity, specificity, and resolution. We can use it to resolve complex functions of the nervous system at high temporal and spatial scales.

Our Services

We can provide transmonosynaptic retrograde labeling, biological labeling of neural stem cell development, and related products.

Developable neurotransmitter probe-like neural stem cells

Name Neurotransmitter probes
hNSC-NE cell line Norepinephrine probe
hNSC-Ach cell line Acetylcholine probe
hNSC-DA cell line Dopamine probe

In the nervous system, neurotransmitters and neuromodulators are mediators of cell-to-cell communication and have broad and important regulatory roles. Monitoring the concentration and dynamics of specific neurotransmitters and neuromodulators with high spatiotemporal precision can provide important information for decoding intercellular communication in neural networks in healthy and diseased states. To enhance performance, these neurotransmitter probe-like neural stem cells offered by Alfa Cytology are continuously being optimized with updated iterations. Please feel free to contact us for the latest news or related service and product inquiries.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.