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Recombinant human BDNF protein, His

Recombinant human BDNF protein, His

CAT#: NRP-N001

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Overview Specification

Species	Human
Tag	His
Expression Systems	E.coli
Keywords	Neural recombinant proteins

Synonyms	Abrineurin; BDNF; BDNF; BDNF_HUMAN; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; MGC34632; MGC34632; Neurotrophin; Recombinant human BDNF protein, His
Description	Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family.
Trait	Lyophilized or liquid
Gene ID	627
SWISS	P23560
Theoretical Molecular Weight	13 kDa
Detection Molecular Weight	14 kDa
Endotoxin	Not analyzed
Purity	>95% as determined by SDS-PAGE
Purification Method	AC
Concentration	＞0.5 mg/ml
Activity	Not tested
Buffer	20 mM Tris-HCl (pH=8.0)
Storage	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Notes	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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