Recombinant human BDNF protein, His
CAT#: NRP-N001
Inquiry
Overview
Specification
| Species
|
Human |
| Tag
|
His |
| Expression Systems
|
E.coli |
| Keywords
|
Neural recombinant proteins |
| Synonyms
|
Abrineurin; BDNF; BDNF; BDNF_HUMAN; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; MGC34632; MGC34632; Neurotrophin; Recombinant human BDNF protein, His |
| Description
|
Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family. |
| Trait
|
Lyophilized or liquid |
| Gene ID
|
627 |
| SWISS
|
P23560 |
| Theoretical Molecular Weight
|
13 kDa |
| Detection Molecular Weight
|
14 kDa |
| Endotoxin
|
Not analyzed |
| Purity
|
>95% as determined by SDS-PAGE |
| Purification Method
|
AC |
| Concentration
|
＞0.5 mg/ml |
| Activity
|
Not tested |
| Buffer
|
20 mM Tris-HCl (pH=8.0) |
| Storage
|
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| Notes
|
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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