Recombinant human NeuN protein, GST & His
CAT#: NRP-N010
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Overview
Specification
Species
|
Human |
Tag
|
GST & His |
Expression Systems
|
E.coli |
Keywords
|
Neural recombinant proteins |
Synonyms
|
RFOX3_HUMAN; RNA binding protein fox-1 homolog 3; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); FOX3; NEUN; FOX-3; HRNBP3 |
Description
|
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
Trait
|
Liquid |
Gene ID
|
146713 |
SWISS
|
A6NFN3 |
Theoretical Molecular Weight
|
38 kDa |
Detection Molecular Weight
|
47 kDa |
Endotoxin
|
Not analyzed |
Purity
|
>95% as determined by SDS-PAGE |
Purification Method
|
AC |
Concentration
|
>0.5 mg/ml |
Activity
|
Not tested |
Buffer
|
20 mM Tris-HCl (pH=8.0) |
Storage
|
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
Notes
|
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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