Recombinant human NGF-β protein (Active, HEK293)
CAT#: NRP-N015
Inquiry
Overview
Specification
| Species
|
Human |
| Tag
|
Tag free |
| Expression Systems
|
HEK293 cell |
| Keywords
|
Neural recombinant proteins |
| Synonyms
|
Beta-NGF Protein, Human；HSAN5 Protein, Human； NGFB Protein, Human；Recombinant human Nerve growth factor;Recombinant human NGF-β protein (Active, HEK293) |
| Description
|
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibit the growth-stimulating activity of NGF protein. The NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system. |
| Trait
|
Lyophilized powder |
| Gene ID
|
4803 |
| SWISS
|
P01138 |
| Theoretical Molecular Weight
|
25 kDa |
| Endotoxin
|
< 0.5 EU/μg as determined by LAL. |
| Purity
|
>95% as determined by SDS-PAGE |
| Purification Method
|
AC |
| Concentration
|
＞0.5 mg/ml |
| Activity
|
Yes |
| Storage
|
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| Notes
|
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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