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Recombinant human NGF-β protein (Active, HEK293)

Recombinant human NGF-β protein (Active, HEK293)

CAT#: NRP-N015

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Overview Specification

Species	Human
Tag	Tag free
Expression Systems	HEK293 cell
Keywords	Neural recombinant proteins

Synonyms	Beta-NGF Protein, Human；HSAN5 Protein, Human； NGFB Protein, Human；Recombinant human Nerve growth factor;Recombinant human NGF-β protein (Active, HEK293)
Description	Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibit the growth-stimulating activity of NGF protein. The NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Trait	Lyophilized powder
Gene ID	4803
SWISS	P01138
Theoretical Molecular Weight	25 kDa
Endotoxin	< 0.5 EU/μg as determined by LAL.
Purity	>95% as determined by SDS-PAGE
Purification Method	AC
Concentration	＞0.5 mg/ml
Activity	Yes
Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
Notes	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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