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Learn MoreReporter cell lines are those stably expressed cell lines tagged with a reporter gene that can be used to visualize, track and isolate the target gene. Reporter cell lines can be generated by exogenous expression driven by the target gene's promoter with an easily detectable tag. However, since the level of exogenous expression may have unpredictable effects on experimental results, researchers prefer an endogenous expression of reporter genes. Reporter cell lines have been widely used in the study of gene expression regulation, signal transduction pathways, and receptor-ligand interactions to track intracellular signaling.
In vitro bioactivity assays are a critical part of antibody drug development. Alfa Cytology offers a stable and affordable tool for brain tumor antibody drug development. We can customize the development of reporter gene functional cell lines to meet customer needs. It can eliminate the need for primary cell culture and overcome the limitations of traditional methods and is suitable for large-scale high-throughput brain tumor antibody drug screening, bioactivity assay, and stability determination.
Immune checkpoint inhibitor | Combination bioassays | Fc receptor bioassay | |
CD47-SIRPa blockade bioassay TIGIT/CD155 blockade bioassay LAG3/MHCII blockade bioassay PD-1/PD-L1 blockade bioassay |
PD-1+TIGIT CD3+CD19 CD3 Bispecific antibody series CD16 Bispecific antibody series |
ADCC reporter bioassay ADCP reporter bioassay |
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Immune checkpoint activation | Cytokine and signaling pathway reporter gene series | ||
GITR activation bioassay 4-1BB activation bioassay OX-40 activation bioassay CD27 activation bioassay CD40 activation bioassay |
NFAT reporter cell line NF-KB reporter cell line NF-KB/AP-1 reporter cell line IL-2 promoter reporter cell line STAT-5 reporter cell line VEGF reporter cell line ANG2 reporter cell line |
Alfa Cytology provides services for the construction of reporter gene functional cell lines for brain tumors, which can be applied to promoter activity studies, transcription factor studies, mammalian cell two-hybrid assays, and live animal imaging experiments. Our experts will save you time and effort and ensure the smooth running of your experiments. Please feel free to contact to communicate project details.