S100 Beta Monoclonal Antibody

CAT#: AST-M005

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Overview Specification

Target	S100 Beta
Cell Type	Types 1 and 2 astrocytes
Host	Mouse
Isotype	IgG1
Applications	WB, IHC, IF, ELISA
Reactivity	Human, mouse, pig, rat
Conjugate	Unconjugated
Keywords	Types 1 and 2 astrocytes; Mouse; IgG1; WB, IHC, IF, ELISA

Product Information	It targets S100 Beta in WB, IHC, IF, ELISA applications and shows reactivity with Human, mouse, pig, rat samples.
Background Information	S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new biomarker for mood disorders.
Synonyms	NEF, Protein S100 B, S 100 protein beta chain, S 100 protein subunit beta, S100, S100 Beta, S100 calcium binding protein B, S100B, S100beta
Full Name	S100 calcium binding protein B
Tested Reactivity	Human, mouse, pig, rat
Cited Reactivity	Human, mouse, rat
Type	Antibody
Class	Monoclonal
Immunogen	S100 Beta fusion protein
Calculated Molecular Weight	11 kDa
Observed Molecular Weight	11 kDa
GenBank Accession Number	BC001766
Gene ID	6285
Gene Symbol	S100B
Form	Liquid
Purification Method	Protein G purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Rat brain tissue, C6 cells, pig brain tissue
Positive IHC Detected	Human malignant melanoma tissue, human appendicitis tissue, mouse brain tissue, rat brain tissue
Positive IF Detected	Rat brain tissue

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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