Tissue Microarray Services for Brain Tumors

Tissue microarrays, like gene microarrays, protein microarrays, and cellular microarrays, belong to a particular, new type of biochip. It is a new high-throughput, multi-sample research tool. It integrates dozens or even thousands of different individual tissue specimens on a single solid-phase carrier, providing a high-throughput, large-sample, and rapid molecular-level analysis tool for brain tumor molecular biology.

Our tissue microarray service for brain tumors

Tissue microarray technology integrates dozens to hundreds of individual tissue specimens on a single solid-phase carrier, providing a high-throughput, large-sample, and rapid molecular-level analysis tool. Alfa Cytology can effectively utilize hundreds or thousands of tissue specimens at a time, either naturally or in the pathological state of brain tumors, to help you investigate the relationship between specific genes and the proteins they express and brain tumors. This can be useful for molecular diagnosis of brain tumors, localization of prognostic indicators and therapeutic targets, and screening antibodies and drugs.

Tissue microarray construction flow for brain tumors

We can do these for you

• Cell phenotyping. Our tissue microarray technology allows us to perform high-throughput immunophenotyping of cells. We use standard immunohistochemistry to test hundreds or even thousands of brain tumor tissue specimens on tissue microarrays for a variety of indicators. Such assays can be used to identify these indicators that are closely related to the diagnosis, differential diagnosis, and prognosis of brain tumors. Moreover, compared to intact large tissue sections, tissue microarrays constructed from spot samples of different sites can then provide a reliable system for high-throughput immunohistochemical phenotyping.
• New gene target screening. Our tissue microarray technology can be used to find new targets for the treatment of brain tumors. Analysis of each candidate gene by tissue microarray can identify the target gene with the most potential to become a new drug or inhibitor or discover new genes that are proto-oncogenes or encode signal transduction molecules. If a specific gene is overexpressed or enhanced in brain tumors, this gene can be an important target gene. Then substances that interfere with the expression of this gene or the function of its expression products may be highly promising new drugs. Therefore, brain tumor tissue microarrays are also suitable for the selection of target genes first when developing anti-tumor drugs.
• Microscopic histological and pathological mapping. We can prepare a variety of microscopic histological and pathological profiles according to your needs. This includes the preparation of various normal tissue microarrays, various pathological types of brain tumor tissue microarrays, etc.
• Gene amplification analysis. We can perform several or dozens of gene amplification and expression assays simultaneously with our tissue microarray technology. It can be used to discover the regulation of various genes in many different brain tumor tissue samples, and then help you to derive valuable experimental results based on this different regulation.
• Antibody screening. The basic approach to antibody and probe testing is to examine a large number of positive and negative tissues from different sources. For this, traditional pathology methods require a large number of single sections. In contrast, we use tissue microarray technology, which can be done in a single experiment.

Applicable research methods

• HE staining
• Immunohistochemistry (IHC) staining
• In situ hybridization (ISH)
• Fluorescence in situ hybridization (FISH)
• In situ PCR
• In situ RT-PCR
• Oligonucleotide-initiated in situ DNA synthesis (PRINS)

Advantages of our technology

• Economic savings. Can help you save a lot of money on your research.
• High throughput. Get a lot of information at once, increasing efficiency hundreds or thousands of times.
• Low error. Consistent experimental conditions provide you with accurate analytical data.
• Parallelization. Highly comparable and accurate.
• Flexible operation. We can set up various experimental controls.

Tissue microarrays have the advantage of combining molecular biology and tissue morphology, overcoming the bottleneck of traditional tissue analysis research. Alfa Cytology has a standardized process and quality control system for the large-scale production of high-throughput tissue microarrays. We combine immunohistochemistry, in situ hybridization, in situ PCR, and other techniques to help you perform morphological and functional studies at different levels of genes, proteins, and cells in the field of brain tumors. Please contact our staff for your custom tissue microarray.