Breast Cancer Cell Line Development Service

Overview of Breast Cancer Cell

Breast cancer (BC) refers to a malignant tumor in which the breast's glandular or ductal epithelial cells become cancerous, ranking first in the incidence of female malignant tumors. Bioengineering techniques are increasingly applied to designing and constructing patient-specific models to understand the unique biological properties of BC and facilitate the research of new therapeutic targets. BC cell models are important and powerful tools for BC research. Much of what researchers know about BC is based on studies of BC cell lines in vivo and in vitro. Although there are more commonly used BC organoid models or animal models, BC cell models are still indispensable in BC research.

Breast cancer cell culture classification by morphological structure. (Witt BL, 2023)

Our Services

Alfa Cytology can provide you with in vitro cell models of BC, including 2D cell lines and 3D spheroids, and we are committed to helping researchers study BC in an efficient, cost-effective, and effective manner. 2D cell culture is the easiest, fastest, and most economical format to study metastasis and invasion. Furthermore, by co-culturing cancer cells with stromal cells, 2D cell culture can be used to mimic signals from tumor microenvironment (TME) tumors and compound screening for antitumor drugs.

The spheroid is the first 3D cancer cell model, and BC 3D spheroid model can more accurately reflect BC tumor biology and tumor microenvironment. Our modeling techniques include static approaches such as scaffold-free methods of hanging drop, liquid overlay on ultra-low attachment plates, and micropatterned plates, and dynamic approaches such as spinner flask, rotating vessels, microfluidic systems or techniques using scaffolds. We will customize the best model for you based on your needs.

Advantages of BC Cell Models

• Homologous, easy to replicate, easy to cultivate
• Infinitely proliferative
• Applicable to a large number of experiments such as high-throughput drug screening

Application Fields

• Compound screening for antineoplastic drugs
• Identify effective and ineffective treatment options for BC
• Highly sensitive and specific predictors of pathological complete response after chemotherapy

Alfa Cytology is an advanced CRO company with years of experience in building BC cell models. Based on our advanced platform and experienced scientists, we can build customized, cost-effective, high-quality BC cell models for BC drug and therapy development research. If you are interested in learning more about our BC cell model services, please contact us. We will provide you with a professional and competitively priced strategy as soon as possible to meet your needs.