Breast Tumor-on-Chip Modeling Services

Breast Tumor-on-Chip Modeling Services

Breast tumor-on-chip modeling uses microfluidic devices to simulate the breast tumor microenvironment, replicating physiological conditions. This approach enables researchers to study cancer biology, drug responses, and tumor-stroma interactions more accurately than traditional 2D cultures. Alfa Cytology offers a comprehensive suite of breast tumor-on-chip modeling services tailored for research and clinical applications.

Introduction of Breast Tumor-on-Chip Models

The breast tumor-on-chip model operates based on principles of physiological simulation, creating an environment closely mirroring natural conditions in breast tissue. Utilizing microfluidic chip systems to mimic the intricate microenvironment of the breast, this model provides a more realistic and biologically relevant platform for investigating breast cancer (BC). The 3D microfluidic model facilitates detailed cellular interactions, offering insights into tumor growth and dissemination mechanisms. The innovative design of breast tumor-on-chip models seeks to deepen our understanding of BC, expedite drug development, and drive personalized medicine research forward. This approach holds the promise of advancing our knowledge and refining our strategies in the fight against BC.

An example of the use of a breast tumor-on-chip.Fig.1 An example of the use of a breast tumor-on-chip. (Subia B, et al., 2021)

Our Services

Alfa Cytology breast tumor-on-chip model features microfluidic chips that facilitate the three-dimensional cultivation of cancerous and non-cancerous breast cells, closely mimicking the actual growth and interaction patterns within the human body. We offer a range of services for your needs:

  • Microfluidic chip design and manufacturing
    We specialize in designing and manufacturing microfluidic chips tailored to simulate the growth environment of breast tissue and tumors.
  • Cell culture and seeding
    We assist you in cultivating both malignant and non-malignant breast on a chip, mimicking the cell interactions and growth in real biological organisms.
  • Drug testing and evaluation
    We support your drug testing efforts on the chip, evaluating the impact of drugs on breast tumors and providing insights into efficacy and potential side effects.
  • Disease modeling
    Our focus is on helping you utilize chip models to study the pathogenesis of BC, exploring a deeper understanding of tumor behavior in microenvironments.

Application Fields

We can design breast tumor-on-chip models based on your requirements, and here are the customizable features:

  • Model the characteristics of subtype-specific breast cells
  • Simulate metastatic BC research
  • Regulate local oxygen concentration, nutrient supply, and cell interactions

Advantages of Our Services

  • Interdisciplinary team collaboration
  • Customized microfluidic chip designs
  • Comprehensive support

Alfa Cytology boasts extensive expertise in BC research garnered over many years. We are committed to continuous innovation, perpetually exploring improved solutions for our clientele, ensuring the delivery of top-notch products and services. If you are interested in learning more about our breast tumor-on-chip modeling services, please don't hesitate to contact us. Our dedicated and knowledgeable staff will promptly get in touch with you.

Reference

  1. Subia B, et al. Breast tumor-on-chip models: From disease modeling to personalized drug screening. J Control Release. 2021 Mar 10; 331: 103-120.
All our services are exclusively intended for preclinical research purposes. They are not intended for diagnostic, therapeutic, or patient management applications.