Small molecule drugs can penetrate cell membranes to target intracellular proteins, and their stability and oral characteristics allow for direct and efficient drug delivery to patients. Compared with biological products, small molecule drugs' pharmacokinetic and pharmacodynamic properties are more predictable, so the corresponding drug treatment regimen is more straightforward. Small molecule drugs play an essential role in breast cancer (BC) therapy.
Fig. 1. Molecular subtypes of breast cancer and types of triple-negative breast cancer. (Islam MR, et al., 2022)
Alfa Cytology can provide you with BC small molecule drug development services. Our services include:
The main pathways for drug target discovery are:
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We mainly obtain leads to compounds by the following methods:
Method | Description |
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Virtual high-throughput screening | Using the mighty computing power of the computer, using the three-dimensional pharmacophore model or the method of molecular docking, it is a method to search for possible active compounds in the compound database. |
DNA-encoded small molecule compound library synthesis and screening technology | Utilizing the method of combinatorial chemistry and the diversity and expandability of DNA coding, it can quickly provide lead compounds for the early decisive stage of drug development, thereby speeding up the development process of new drugs. |
We can provide you with comprehensive pharmacology and toxicology tests of BC drugs, including non-clinical tests of drug efficacy, safety pharmacology tests, single-dose toxicity tests, repeated-dose toxicity tests, genetic toxicity tests, reproductive toxicity tests, carcinogenicity tests, etc.
Our services include the synthesis process of raw materials, the quality research of raw materials, the stability research of raw materials, the research of preparations, the research of excipients, the stability research of preparations, etc.
Alfa Cytology is driven by R&D and innovation, focusing on the development of small-molecule drugs. Our team is composed of highly educated and high-quality professionals with good professional backgrounds and experience in BC research. We have a complete set of technologies including small molecule screening, synthesis, drug analysis, stability research, and preparation development. If you are interested in learning more about our BC therapy development services, please feel free to contact us. Our professional and patient staff will get in touch with you as soon as possible.
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