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Learn MoreHarnessing the power of dendritic cells (DCs) in cancer immunotherapy requires accurate and reliable assays to evaluate their activation, cytokine profiles, and overall functionality. Alfa Cytology offers a wide range of services tailored to the evaluation of dendritic cell activation and cytokine profiles.
Fig.1 Regulation of DC function by tumours. (Wculek, S. K., et al., 2020)
At Alfa Cytology, we offer a comprehensive range of dendritic cell-based assays tailored to meet the diverse needs of our clients in the pharmaceutical and biotechnology industries. Our services include, but are not limited to:
Dendritic Cell Isolation and Characterization
Our experienced team utilizes optimized protocols to ensure the purity and viability of isolated DC populations. Through flow cytometry and functional assays, we comprehensively characterize these cells, assessing their phenotype, maturation status, and antigen-presenting capabilities.
Antigen Presentation Assays
We offer a range of antigen presentation assays that allow for the evaluation of DC-mediated immune activation. Our assays include both in vitro and in vivo models, enabling the assessment of various aspects of antigen presentation, such as cross-presentation, cytokine production, and T cell priming.
Cell Interactions and Co-culture Assays
By employing imaging techniques, molecular profiling, and functional assays, we decipher the intricate cross-talk, facilitating a comprehensive understanding of immune regulation and immunomodulatory interventions.
By assessing the activation requirements and cytokine profiles of dendritic cells, these assays provide crucial insights into the immunomodulatory potential of novel therapeutic agents. Alfa Cytology offers comprehensive services in dendritic cell-based assays, enabling accurate and predictive evaluation of immunotherapies. If you are interested in our service, please contact us for more details.
Reference
For research use only.