Disseminated Tumor Model Development Services

Using state-of-the-art technology and a deep understanding of tumor biology, Alfa Cytology focuses on creating models that accurately mimic human disease progression. We offer comprehensive solutions for the development of disseminated tumor models designed to replicate the complex nature of metastatic cancer, providing a powerful platform for evaluating the efficacy and safety of new therapeutic agents.

Introduction to the Disseminated Tumor Model

Disseminated tumor model is a sophisticated preclinical tool designed to mimic the process of metastasis, where cancer cells spread from the primary tumor site to distant organs. Unlike traditional tumor models that focus solely on primary tumor growth, disseminated tumor models provide a comprehensive understanding of cancer behavior by simulating the complex dynamics of metastatic disease. This model is crucial for studying the later stages of cancer progression, which are often the most challenging to treat and are responsible for the majority of cancer-related deaths.

Fig.1 The interaction of immune cells and disseminated tumor cells (DTCs). (Peng, L., et al., 2021)

The Applications of the Disseminated Tumor Model

Our Services

Alfa Cytology provides a powerful translational platform for studying metastatic disease and advancing the development of effective cancer therapies. Our comprehensive dissemination tumor model development services involve model creation, maintenance and therapeutic testing. We follow the latest research and industry standards to ensure high quality and reproducible results that meet the specific needs of research institutions and pharmaceutical companies.

Model Screening and Customization Service

Helping clients select the most appropriate dissemination tumor model from a broad portfolio of products and providing customization services.

Advanced Imaging Service

Utilization of bioluminescence imaging (BLI) with luciferase-enabled cell lines allows for precise monitoring and staging of study cohorts, systemic tumor burden assessment, and quantitative evaluation of drug responses over time.

Tumor Transplantation Methods

Service Process for Disseminated Tumor Model Development

Collaborate with clients to design a customized disseminated tumor model strategy based on their specific research objectives.

Project Design

Verify successful tumor engraftment through initial monitoring using imaging techniques and regular assessments of tumor growth and animal health.

Monitoring and Verification

Model Establishment

Select appropriate tumor sources and establish the model through precise transplantation methods such as intravenous or orthotopic injections.

Data Analysis and Reporting

Perform detailed data analysis, including histopathology and molecular profiling, and provide a comprehensive report to the client.

Alfa Cytology provides advanced preclinical services to address key challenges encountered in the field of cancer therapy development. With extensive experience in a wide range of cancer models as well as expertise in the field of oncology and microenvironment, we offer stock model products, model customization and co-development services to meet the precise needs of our clients. Please let us know your project requirements and we will provide you with comprehensive services from solution to report. If you have any questions, please contact us.

For research use only.