Immune-mediated Tumor Killing Assays
At Alfa Cytology, we offer a comprehensive panel of immune-mediated tumor killing assays that enable the evaluation of immunotherapies' ability to modulate T cell activity and aid in our clients' oncology programs.
Introduction to Immune-mediated Tumor Killing Assays
Cancer immunotherapy has emerged as a promising approach in the fight against cancer, harnessing the power of the immune system to target and eliminate tumor cells. Understanding the mechanisms underlying immune cell-mediated tumor killing is crucial for the development of effective immunotherapeutic strategies.
- Unleashing the Potential of Immunotherapies
Immune-based tumor killing tests are key for measuring how well immune cells can destroy cancer cells, offering insights into the potential of immunotherapies.
- Mimicking Complex Interactions
Immune-mediated tumor killing assays aim to closely mimic these interactions in vitro, thereby enabling researchers to study the dynamic processes involved in immune cell-mediated cytotoxicity.
- Personalizing Cancer Treatment
By assessing the potency of immune cells against patient-derived tumor cells, these assays facilitate the development of personalized treatment approaches.
Our Services
At Alfa Cytology, we offer a comprehensive range of immune-mediated tumor killing assays designed to assess the efficacy and immunomodulatory function of test compounds and antibodies. Our assays utilize state-of-the-art techniques, providing high sensitivity, quantitative analysis, and the ability to monitor tumor cell death over time. Our services include, but are not limited to:
T Cell Killing Assay
Our specialized in vitro T cell killing assay allows for the evaluation of T cell cytotoxicity-mediated killing. By utilizing a 96-well plate co-culture system comprising human tumor cells and primary immune cells, we enable the kinetic monitoring of the killing immune response towards tumor cells.
Antibody-Dependent Cell Cytotoxicity (ADCC) Assay
By utilizing primary immune cells and live cell imaging, we offer a sensitive and quantitative approach to evaluate the immunomodulatory function of antibodies and their ability to engage effector immune cells in tumor cell killing.
Spheroid Immune-Mediated Tumor Killing Assays
We offer assays that assess the killing efficiency of T cells against tumor cell aggregates, known as organoids. By quantifying the increase in killed cells and comparing the percentage of cell death before and after T cell treatment, we can determine the potency of T cells in targeting cancer cell clusters.
Immune-mediated tumor killing assays are instrumental in evaluating the efficacy of immunotherapies and understanding the dynamics of immune cell interactions with tumor cells. Alfa Cytology offers a comprehensive range of services in immune-mediated tumor killing assays. With a focus on providing unparalleled insights, we empower researchers and pharmaceutical companies to advance their oncology programs. If you are interested in our service, please contact us for more details.
For research use only.
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