Immune-mediated Tumor Killing Assays
At Alfa Cytology, we offer a comprehensive panel of immune-mediated tumor killing assays that enable the evaluation of immunotherapies' ability to modulate T cell activity and aid in our clients' oncology programs.
Introduction to Immune-mediated Tumor Killing Assays
Cancer immunotherapy has emerged as a promising approach in the fight against cancer, harnessing the power of the immune system to target and eliminate tumor cells. Understanding the mechanisms underlying immune cell-mediated tumor killing is crucial for the development of effective immunotherapeutic strategies.
- Unleashing the Potential of Immunotherapies
Immune-based tumor killing tests are key for measuring how well immune cells can destroy cancer cells, offering insights into the potential of immunotherapies.
- Mimicking Complex Interactions
Immune-mediated tumor killing assays aim to closely mimic these interactions in vitro, thereby enabling researchers to study the dynamic processes involved in immune cell-mediated cytotoxicity.
- Personalizing Cancer Treatment
By assessing the potency of immune cells against patient-derived tumor cells, these assays facilitate the development of personalized treatment approaches.
Our Services
At Alfa Cytology, we offer a comprehensive range of immune-mediated tumor killing assays designed to assess the efficacy and immunomodulatory function of test compounds and antibodies. Our assays utilize state-of-the-art techniques, providing high sensitivity, quantitative analysis, and the ability to monitor tumor cell death over time. Our services include, but are not limited to:
T Cell Killing Assay
Our specialized in vitro T cell killing assay allows for the evaluation of T cell cytotoxicity-mediated killing. By utilizing a 96-well plate co-culture system comprising human tumor cells and primary immune cells, we enable the kinetic monitoring of the killing immune response towards tumor cells.
Antibody-Dependent Cell Cytotoxicity (ADCC) Assay
By utilizing primary immune cells and live cell imaging, we offer a sensitive and quantitative approach to evaluate the immunomodulatory function of antibodies and their ability to engage effector immune cells in tumor cell killing.
Spheroid Immune-Mediated Tumor Killing Assays
We offer assays that assess the killing efficiency of T cells against tumor cell aggregates, known as organoids. By quantifying the increase in killed cells and comparing the percentage of cell death before and after T cell treatment, we can determine the potency of T cells in targeting cancer cell clusters.
Immune-mediated tumor killing assays are instrumental in evaluating the efficacy of immunotherapies and understanding the dynamics of immune cell interactions with tumor cells. Alfa Cytology offers a comprehensive range of services in immune-mediated tumor killing assays. With a focus on providing unparalleled insights, we empower researchers and pharmaceutical companies to advance their oncology programs. If you are interested in our service, please contact us for more details.
! For research use only.
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