Custom 2D and 3D Cell Culture Models of Leukemia

While cell culture has played a significant role in drug and disease research pertaining to leukemia, it is crucial to acknowledge the limitations associated with 2D cell culture. To better simulate the in vivo environment and obtain more realistic data, the emergence of 3D cell culture technology has been explored. 3D cell culture provides a closer representation of the tumor microenvironment.

Alfa Cytology offers customized 2D and 3D cell models of leukemia, along with comprehensive 3D cell culture technology and platforms. By leveraging our services, you gain access to both 2D and 3D cell culture options, allowing for a deeper understanding of complex biological systems and a more effective study of the molecular mechanisms involved in leukemia.

Function Roles of 3D Cell Models of Leukemia

The selection of an experimental model significantly impacts the therapeutic outcomes of subsequent clinical trials. Traditional 2-dimensional cell culture in vitro cannot accurately reveal pharmacology and pharmacokinetics. The 3D cell model provides a closer representation of the in vivo tumor environment, allowing for the study of cell distribution, migration, and cell-cell interactions. In contrast to 2D cell culture, 3D cell culture techniques employ natural or artificial extracellular matrix and scaffolds to cultivate cells within a 3D environment.

Fig. 1. Schematic of a direct 3 Dimensional (3D) co-culture model of acute myeloid leukemia (AML) cells and stromal cells. (Syama, K. et al., 2021)

To more accurately simulate the tumor microenvironment in vitro, Alfa Cytology provides comprehensive leukemia 2D and 3D cell culture model services, including but not limited to the following.

2D Culture for Leukemia Research

We provide a basic 2D culture service and a 2D cell culture system to support your cell experiment. Due to our expertise and proficiency in 2D cell culture, our 2D cell culture services offer a competitive price advantage. By selecting our 2D cell culture service, we can conduct a range of leukemia research experiments and leukemia drug testing based on the 2D cell culture platform. We will deliver reliable experimental results.

Custom 3D Models of Leukemia

According to your research needs, we will design reasonable experimental protocols, customize 3D cell models, and design the most appropriate models for you to help you with your drug development process.

Co-culture Methods for Leukemia Research

We also offer 2D and 3D co-culture methods for leukemia research, including direct co-culture, indirect co-culture, and 3D co-culture.

Custom Organoid Models of Leukemia

Our services encompass organoids and customized solutions tailored for leukemia research. Organoids not only replicate the structural and functional characteristics of leukemic tissues or organs but also facilitate the development of therapeutic drugs.

Custom Spheroid Cultures of Leukemia

We can provide spheroid culture models of leukemia, and customize different leukemia spheroid models. We offer a culture method that closely mimics the human body, aiming to obtain experimental results that closely resemble the tumor microenvironment.

Advantages of Our Service

• We provide advanced 2D and 3D cell culture techniques and services to facilitate your study of the leukemia cell microenvironment.
• We have a mature leukemia 3D cell culture platform to support your drug research.
• We provide a complete leukemia cell model solution to speed up your drug development process.
• We provide a complete set of services from the model design of leukemia 3D cells to the completion of experiments to shorten your research time.

Alfa Cytology provides 3D cell models of leukemia, uses a combination of these models, and integrates them with other experimental approaches to gain a comprehensive understanding of leukemia pathogenesis and develop effective therapeutic strategies. If you have any questions or would like more information about our services, please feel free to contact us.