AP1153 aptamer sodium

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Catalog No.: PC0171

Size: 50 mg, 100mg, 250mg

Description

AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM) but does not activate CCKBR-related signaling pathways. The sodium AP1153 aptamer is internalized by pancreatic ductal adenocarcinoma cells (PDAC) in a receptor-mediated manner and can be bioconjugated to fluorescent nanoparticle surfaces to facilitate in vivo delivery of nanoparticles to PDAC tumors.

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Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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