CU-T12-9

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Catalog No.: PC0182

Size: 1 mg, 5 mg,10 mg, 50 mg, 100 mg, 200 mg

Description

CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.

Molecular Weight	362.31
Formula	C17H13F3N4O2
CAS No.	1821387-73-8
Appearance	Solid
Color	Light yellow to yellow
SMILES	CNC1=CC=C(C=C1N2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F)[N+]([O-])=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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