DSL6A/C1

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Catalog No.: PC0008

Description

DSL6A/C1 is derived from transplantable acinar cell carcinoma (DSL-6) established from primary pancreatic cancer in diazaserine-treated Lewis rats. Expression of the ductal cell marker OC.2 is shown along with subpopulations expressing the ductal markers OV-6, CK-7, and CK-19. DSL6A/C1 cells have been reported to be tumorigenic in Lewis rats and produce solid tumors composed of duct-like structures surrounded by dense fibrous tissue. This cell line lost structural and immunohistochemical acinar cell markers during culture and retransplantation, while acquiring ductal cell markers.

Origin	Rat pancreatic carcinoma
Application	Study of pancreatic carcinomas, differentiation of acinar/ductal cells.
Biological Source	Rat pancreas
Growth Mode	Adherent
Karyotype	Not specified
Morphology	Polygonal
Products	Expresses CFTR protein
Receptors	Lacks CCK-A receptors
Technique	Cell culture, suitable for mammals.
Relevant Disease	Cancer
Shipped In	Dry ice
Culture Medium	Waymouth′s MB 752/1 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).

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