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KRAS G12C inhibitor 47

KRAS G12C inhibitor 47

KRAS G12C inhibitor 47

Catalog No.: PC0077

Size: 50 mg, 100mg, 250mg.


Description

KRAS G12C inhibitor 47 is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 47 showed p-ERK inhibitory activity in MIA PaCA-2 and A549 cells with IC50 of 0.046 and 69.8 µM, respectively. KRAS G12C inhibitor 47 has the potential to be studied in pancreatic, colorectal, and lung cancers.

Molecular Weight 547.02
Formula C30H28ClFN4O3
CAS No. 2253119-24-1
SMILES O=C1N=C(N2CCN(CC2)C(C=C)=O)C3=C(N1C4=C(C(C)C)C=CC=C4)C=C(C5=C(O)C=CC=C5F)C(Cl)=C3
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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