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KRAS inhibitor-12

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KRAS inhibitor-12

KRAS inhibitor-12

Catalog No.: PC0065

Size: 50 mg, 100mg, 250mg.

Description

KRAS inhibitor-12 is a potent KRAS G12C inhibitor with an IC50 of 0.537 µM. KRAS inhibitor-12 exhibits p-ERK inhibitory activity in MIA PaCA-2 and A549 cells with IC50 of 1.3 and 3.7 µM, respectively. KRAS inhibitor 12 has the potential to be studied in pancreatic, colorectal, and lung cancers.

Molecular Weight 452.33
Formula C19H16Cl2FN5OS
CAS No. 2230874-00-5
SMILES O=C(N1CCN(CC1)C2=C3C=C(Cl)C(C4=C(Cl)C=CC(N)=N4)=C(F)C3=NS2)C=C
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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