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KRAS inhibitor-13

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KRAS inhibitor-13

KRAS inhibitor-13

Catalog No.: PC0063

Size: 50 mg, 100mg, 250mg.

Description

KRAS inhibitor-13 is a potent KRAS G12C inhibitor with an IC50 of 0.883 µM. KRAS inhibitor-13 exhibits p-ERK inhibitory activity in MIA PaCA-2 and A549 cells, with IC50 of 5.9 and >100 µM respectively. KRAS inhibitor 13 has the potential to study pancreatic, colorectal, and lung cancer.

Molecular Weight 479.95
Formula C25H19ClFN3O2S
CAS No. 2230873-96-6
SMILES C=CC(N1[C@]2([H])[C@@](CC1)([H])N(C3=C4C(C(F)=C(C5=CC(O)=CC6=C5C=CC=C6)C(Cl)=C4)=NS3)C2)=O
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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