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KRAS inhibitor-14

KRAS inhibitor-14

Catalog No.: PC0066

Size: 50 mg, 100mg, 250mg.


Description

KRAS inhibitor-14 is a potent KRAS G12C inhibitor. KRAS inhibitor-14 exhibits p-ERK inhibitory activity in MIA PaCA-2 and A549 cells, with IC50 of 1.12 and >33.3 µM respectively. KRAS inhibitor-14 has the potential to study pancreatic, colorectal, and lung cancer.

Molecular Weight 486.77
Formula C20H15Cl3FN3O2S
CAS No. 2230873-78-4
SMILES C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(O)=CC(Cl)=C4Cl)=C(C3=NS2)F)Cl)=O
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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