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KRAS inhibitor-15

KRAS inhibitor-15

Catalog No.: PC0067

Size: 50 mg, 100mg, 250mg.


Description

KRAS inhibitor-15 is a potent KRAS G12C inhibitor with an IC50 of 0.954 µM. KRAS inhibitor-15 exhibits p-ERK inhibitory activity in MIA PaCA-2 and A549 cells, with IC50 of 2.03 and >33.3 µM respectively. KRAS inhibitor-15 has the potential to study pancreatic, colorectal and lung cancers.

Molecular Weight 451.34
Formula C20H17Cl2FN4OS
CAS No. 2230873-75-1
SMILES C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(N)=CC=C4Cl)=C(C3=NS2)F)Cl)=O
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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