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KRAS inhibitor-16

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KRAS inhibitor-16

KRAS inhibitor-16

Catalog No.: PC0068

Size: 50 mg, 100mg, 250mg.

Description

KRAS inhibitor-16 is a potent KRAS G12C inhibitor with an IC50 of 0.457 µM. KRAS inhibitor-16 showed p-ERK inhibitory activity in MIA PaCA-2 and A549 cells, with IC50 of 3.06 and 11.1 µM respectively. KRAS inhibitor-16 has the potential to study pancreatic, colorectal, and lung cancer.

Molecular Weight 452.33
Formula C20H16Cl2FN3O2S
CAS No. 2230873-67-1
SMILES C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(O)=CC=C4Cl)=C(C3=NS2)F)Cl)=O
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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As science and technology continue to evolve, Alfa Cytology, as a provider of preclinical research services, is committed to maintaining the pace of progress, providing pancreatic cancer-related solutions that leverage existing resources to help our customers accelerate research and development.

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