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PNC-28 acetate

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PNC-28 acetate

PNC-28 acetate

Catalog No.: PC0189

Size: 1 mg, 5 mg,10 mg, 50 mg, 100 mg

Description

PNC-28 acetate is a peptide derived from the mdm-2 binding domain (residues 17-26) of the p53 protein and contains a transmembrane penetrating sequence. PNC-28 acetate could be used in pancreatic cancer research.

Molecular Weight 3509.13 (free acid)
Formula C164H255N47O37S.xC2HF3O2
Appearance Solid
Color White to off-white
Sequence Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
In Vitro PNC-28 (0-0.5 mg/mL) blocks growth of a lethal human pancreatic cancer cell line.
In Vivo PNC-28 (2 mg/mouse, SC or IP, for 14 days) blocks the growth of BMRPA1. Tuc3 cells in vivo.
PNC-28 (1-20 mg/mouse, SC, for 14 days) inhibits BMRPA1. Tuc3 tumor growth especially if delivered directly to the tumor .
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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