PNC-28 acetate

Products

Quote Request

Catalog No.: PC0189

Size: 1 mg, 5 mg,10 mg, 50 mg, 100 mg

Description

PNC-28 acetate is a peptide derived from the mdm-2 binding domain (residues 17-26) of the p53 protein and contains a transmembrane penetrating sequence. PNC-28 acetate could be used in pancreatic cancer research.

Molecular Weight	3509.13 (free acid)
Formula	C164H255N47O37S.xC2HF3O2
Appearance	Solid
Color	White to off-white
Sequence	Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
*In Vitro*	PNC-28 (0-0.5 mg/mL) blocks growth of a lethal human pancreatic cancer cell line.
*In Vivo*	PNC-28 (2 mg/mouse, SC or IP, for 14 days) blocks the growth of BMRPA1. Tuc3 cells in vivo. PNC-28 (1-20 mg/mouse, SC, for 14 days) inhibits BMRPA1. Tuc3 tumor growth especially if delivered directly to the tumor .

All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.