Rineterkib hydrochloride

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Rineterkib hydrochloride

Catalog No.: PC0106

Size: 5 mg,10 mg, 25 mg,50 mg, 100 mg, 200 mg, 500 mg

Description

Rineterkib Hydrochronide is an oral ERK1 and ERK2 inhibitor indicated for the treatment of proliferative diseases characterized by activating mutations in the MAPK pathway. This activity is particularly relevant for the treatment of KRAS -mutant NSCLC, BRAF -mutant NSCLC, KRAS -mutant pancreatic cancer, KRAS -mutant colorectal cancer (CRC), and KRAS -mutant ovarian cancer.

Formula	C26H28BrClF3N5O2
CAS No.	1715025-34-5
Appearance	Solid
Color	White to yellow
SMILES	O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F.[H]Cl.[x]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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