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Rineterkib

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Rineterkib

Rineterkib

Catalog No.: PC0105

Size: 1 mg, 5 mg,10 mg, 50 mg, 100 mg, 200 mg, 500 mg

Description

Rineterkib is an oral ERK1 and ERK2 inhibitor indicated for the treatment of proliferative diseases characterized by activating mutations in the MAPK pathway. This activity is particularly relevant for the treatment of KRAS -mutant NSCLC, BRAF -mutant NSCLC, KRAS -mutant pancreatic cancer, KRAS -mutant colorectal cancer (CRC), and KRAS -mutant ovarian cancer.

Molecular Weight 578.42
Formula C26H27BrF3N5O2
CAS No. 1715025-32-3
Appearance Solid
Color White to light yellow
SMILES O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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