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RORγ antagonist 1

RORγ antagonist 1

Catalog No.: PC0093

Size: 50 mg, 100mg, 250mg.


Description

RORγ Antagonist 1 is a potent betulinic acid derivative that is an antagonist of RORγ. RORγ antagonist 1 exhibits antiproliferative activity in a HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits the RAS/MAPK and AKT/mTORC1 pathways and induces caspase-dependent apoptosis in pancreatic cancer cells.

Molecular Weight 540.86
Formula C35H60N2O2
SMILES O[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(C)CC[C@]5(C(NCCCN(C)C)=O)[C@]4([H])[C@H](C(C)=C)CC5)([H])C1(C)C
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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