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SHP2-IN-22

SHP2-IN-22

Catalog No.: PC0045

Size: 50 mg, 100mg, 250mg.


Description

SHP2-IN-22 is an allosteric inhibitor of SHP2 with an IC50 value of 17.7 nM. SHP2-IN-22 inhibits proliferation, migration, and invasion of MIA PaCa-2 pancreatic cancer cells. SHP2-IN-22 is useful in Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research.

Molecular Weight 497.38
Formula C23H22Cl2N8O
CAS No. 2802453-88-7
SMILES N/C(N1CCN(CC1)C2=CN=C(C(N)=N2)C3=CC=CC(Cl)=C3Cl)=N\C4=CC(OC)=C(C=C4)C#N
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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