TGP 49

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Catalog No.: PC0007

Description

TGP 49 has been isolated from acinar cell carcinomas arising in the pancreas of transgenic Tg(E1a-1-SV40E)Bri18 mice. These mice carry a pseudogene construct consisting of a pancreatic-specific elastase 1 promoter linked to the SV40T antigen, thereby representing an animal model of pancreatic carcinogenesis. TGP 49 secretes small amounts of somatostatin and is one of a series of cell lines isolated from pancreatic tumors deposited at ECACC. They are reported not to secrete amylase or lipase but do secrete trypsin.

Origin	Mouse pancreatic acinar carcinoma
Application	Study of endocrine pancreas carcinomas, hormone assays.
Biological Source	Mouse pancreas
Growth Mode	Adherent
Karyotype	Not specified
Morphology	Trabecular
Products	Somatostatin (low levels)
Receptors	Not specified
Technique	Cell culture, suitable for mammals.
Relevant Disease	Cancer
Shipped In	Dry ice
Culture Medium	DMEM:Ham′s F12 (1:1) + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).

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