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Zamaporvint

Zamaporvint

Catalog No.: PC0074

Size: 5 mg,10 mg, 25 mg,50 mg, 100 mg, 200 mg, 500 mg


Description

Zamaporvint is an orally active, selective Wnt inhibitor. Zamaporvint targets the membrane-bound ortho-acyltransferase Porcupine and inhibits Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays favorable pharmacokinetic profiles and potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines.

Molecular Weight 439.39
Formula C21H16F3N7O
CAS No. 1900754-56-4
Appearance Solid
Color White to off-white
SMILES O=C(CN1C=NC(C2=CC(C(F)(F)F)=NC=C2)=C1C)NC3=NC=C(C4=CN=CC=N4)C=C3
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.