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Zamaporvint

Zamaporvint

Catalog No.: PC0074

Size: 5 mg,10 mg, 25 mg,50 mg, 100 mg, 200 mg, 500 mg


Description

Zamaporvint is an orally active, selective Wnt inhibitor. Zamaporvint targets the membrane-bound ortho-acyltransferase Porcupine and inhibits Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays favorable pharmacokinetic profiles and potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines.

Molecular Weight 439.39
Formula C21H16F3N7O
CAS No. 1900754-56-4
Appearance Solid
Color White to off-white
SMILES O=C(CN1C=NC(C2=CC(C(F)(F)F)=NC=C2)=C1C)NC3=NC=C(C4=CN=CC=N4)C=C3
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
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