Blood-Based Analysis Service for Bladder Cancer

Blood-Based Analysis Service for Bladder Cancer

Blood-based liquid biopsy refers to the analysis of various biomarkers in the blood to obtain information about the presence, characteristics, and progression of a disease, such as bladder cancer. Alfa Cytology provides comprehensive blood -based analysis services for bladder cancer and assists our customers in achieving their goals.

Blood-based Liquid Biopsy in Bladder Cancer

Bladder cancer (BC) presents a significant challenge worldwide, characterized by late diagnosis, poor prognosis, and low survival rates. Traditional diagnostic and monitoring methods like cystoscopy and tissue biopsy have limitations due to tumor heterogeneity, aggressiveness, high cost, and limited suitability for long-term surveillance. However, in recent years, there has been growing interest in the use of liquid biopsies, particularly blood-based analysis, for the discovery of BC biomarkers.

Fig.1 Overview of clinical examination methods for bladder cancer and laboratory analytical techniques for liquid biopsies.Fig.1 Overview of clinical examination methods for bladder cancer and laboratory analytical techniques for liquid biopsies. (Li S., et al. 2023)

Liquid biopsies, including blood-based analysis, provide a noninvasive and efficient approach to identify biomarkers for BC. Extensive research has focused on various liquid biopsy biomarkers, and they have shown promising results in several key applications for BC, including early detection, identification of microscopic residual disease, prediction of recurrence, and assessment of treatment response.

Our Services

Alfa Cytology specializes in providing comprehensive blood-based analysis services for bladder cancer. Our goal is to assist our customers in obtaining crucial information about the presence, characteristics, and progression of the disease. Through our advanced liquid biopsy techniques, we analyze various biomarkers to deliver accurate and actionable insights.

Analyzed Targets Analysis Methods Applications

Analytical Services of CTCs.

CTCs Cell count, genetic profiling by NGS Epigenetic changes
Mutational profiles
Personalized therapy
Therapeutic resistance
Tumor subtyping
Genome mapping

Analytical Services of cfDNA/ctDNA.

cfDNA/ctDNA ddPCR, sequencing by NGS

Analytical Services of cfRNA.

cfRNA Measuring mRNA or miRNA by qPCR, NGS or microarray

Analytical Services of Exosomes.

Exosomes Content profiling using qPCR, NGS or microarray

Metabolomics and Proteomic Analytical Services.

Metabolomics
proteomic
GC-MS、LC-MS、NMR

Advantages of Blood-based Liquid Biopsy

Real-time Monitoring
Longitudinal monitoring of tumor
dynamics and treatment response.

Non-Invasive and Patient-Friendly
Blood samples can be easily obtained.

Services

Tumor Heterogeneity
Analyze different tumor cell populations.

Accessibility
Blood samples from bladder cancer patients in various stages are readily available.

Personalized Medicine
Blood-based liquid biopsy provides information on the molecular profile of tumors.

Contact Us

At Alfa Cytology, we are committed to providing high-quality blood-based analysis services for bladder cancer research. Our experienced team of experts and cutting-edge technologies ensure accurate and reliable results. Contact us today to learn more about our comprehensive services and how we can assist you in achieving your bladder cancer research goals.

Reference

  1. Li, S., Xin, K., and et al. Blood-based liquid biopsy: insights into early detection, prediction, and treatment monitoring of bladder cancer. Cell Mol Biol Lett. 2023, 28, 28.
For research use only. Not intended for any clinical use.
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Alfa Cytology is dedicated to drug development and preclinical services for bladder cancer.

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