Spatial Omics Profiling Services for Bladder Cancer

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Spatial omics profiling is a cutting-edge technique that combines high-resolution imaging and omics technologies to analyze the spatial distribution of molecules within tissues or organisms. Alfa Cytology provides spatial omics profiling services to analyze the spatial organization of biological molecules within the bladder tissue, enabling a deeper understanding of the disease and paving the way for early diagnosis and targeted therapies.

Spatial Omics in Bladder Cancer

Bladder cancer is one of the most common malignancies worldwide, with a high recurrence rate and limited treatment options. Traditional methods of studying bladder cancer have focused on bulk analysis, which overlooks the spatial heterogeneity present within the tumor microenvironment. However, recent advances in spatial omics profiling techniques have revolutionized our understanding of complex diseases like bladder cancer by providing spatially resolved molecular information.

Fig.1 Schematics of the spatial multi-omics technologies and analysis workflow. (Hsieh W. C., et al. 2022)

These spatial omics profiling techniques have revealed previously unrecognized heterogeneity, biomarker signatures, and therapeutic targets within bladder tumors. The spatially resolved molecular information obtained from these techniques is helping to guide personalized therapeutic strategies and the development of novel therapeutics for bladder cancer.

Our Services

At Alfa Cytology, we recognize the importance of spatial omics profiling in unraveling the intricate molecular landscape of bladder cancer. Our team of highly skilled experts is dedicated to providing superior services and solutions that accelerate research projects and contribute to the development of promising applications for bladder cancer.

Spatial Transcriptomics
By capturing the spatial distribution of transcripts, we identify distinct cell populations within the tumor microenvironment and uncover novel molecular signatures associated with bladder cancer progression.

In Situ Sequencing
We offer comprehensive in situ sequencing services for bladder cancer research, providing post-processed images, x-y coordinates of all spots/signals, and optional delivery of RAW images.

Spatial Proteomics
Our spatial proteomics, using advanced techniques like CODEX, enables the simultaneous analysis of multiple proteins within bladder cancer tissues.

Advanced FISH Technologies
Our fluorescence in situ hybridization (FISH) technologies services include the design and delivery of DNA/RNA FISH oligonucleotide probes against a species of interest.

Spatial Mass Spectrometry
We offer spatial mass spectrometry services, enabling the localization, identification, and quantification of molecules such as drugs, metabolites, neurotransmitters, lipids, peptides, and small proteins directly in tissue sections.

Our Services Will Help You Achieve the Following Goals:

Measuring Viral Vector Target Specificity
Assessing Tissue Penetration of Targeted Cancer Agents

Tumor Microenvironment Analysis
Spatial Drug Response Mapping

Contact Us

Alfa Cytology is your trusted partner in advancing bladder cancer research through our single-cell omics profiling services. Our expertise, cutting-edge technologies, and comprehensive service portfolio enable researchers to unravel the complexity of bladder tumors, study cellular heterogeneity, and identify novel therapeutic targets. Contact us today to discuss your bladder cancer research.

Reference

Hsieh W. C., Budiarto B. R., and et al. Spatial multi-omics analyses of the tumor immune microenvironment. J Biomed Sci. 2022, 29, 96.

For research use only. Not intended for any clinical use.

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* Please note that we are not a pharmacy or clinic, so we do not offer diagnostic and treatment services for patients.

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