BMI1 Polyclonal Antibody

CAT#: NSC-P002

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Overview Specification

Target	BMI1
Cell Type	NSCs
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, CoIP, ChIP, ELISA
Reactivity	Human, mouse
Conjugate	Unconjugated
Keywords	NSCs; Rabbit; IgG; WB, IP, IHC, IF, CoIP, ChIP, ELISA

Product Information	It targets BMI1 in WB, IP, IHC, IF, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse samples.
Background Information	BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody detected proteins of 45-48kda, which may include phosphorylated isoforms of the protein.
Synonyms	BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Full Name	BMI1 polycomb ring finger oncogene
Tested Reactivity	Human, mouse
Cited Reactivity	Human, mouse
Class	Polyclonal
Type	Antibody
Immunogen	BMI1 fusion protein
Calculated Molecular Weight	37 kDa
Observed Molecular Weight	37-43 kDa
Gene ID	648
GenBank Accession Number	BC011652
Gene Symbol	BMI1
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	U-937 cells, HEK-293 cells, NCCIT cell, mouse brain tissue, K-562 cells
Positive IP Detected	U-937 cells
Positive IHC Detected	Human liver cancer tissue
Positive IF Detected	HepG2 cells

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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