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FITC-Labeled Human MSLN/Mesothelin Protein (C-hFc)

FITC-Labeled Human MSLN/Mesothelin Protein (C-hFc)

CAT#: CAR-T004

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Overview Specification

Species	Human
Tag	C-hFc
Expression Systems	Expi293
Keywords	Human; C-hFc; Expi293

Synonyms	MSLN; CAK1; Mesothelin; MPF; MPFSMRP; SMR
Background	Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene. Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31 kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. A knockout mouse line that lacks mesothelin reproduces and develops normally.
Source	Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Glu296-Gly580.
Molecular Weight	The protein has a predicted MW of 59 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.
Endotoxin	Less than 1 EU per μg by the LAL method.
Purity	>95% as determined by Tris-Bis PAGE.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage	Valid for 12 months from date of receipt when stored at -80℃.
Notes	Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.

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