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Learn MoreCAT#: CAR-T003
Species | Human |
Tag | C-His-Avi |
Expression Systems | Expi293 |
Keywords | Human; C-His-Avi; Expi293 |
Synonyms | MSLN; CAK1; Mesothelin; MPF; MPFSMRP; SMR |
Background | Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene. Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31 kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. A knockout mouse line that lacks mesothelin reproduces and develops normally. |
Source | Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Glu296-Gly580. |
Molecular Weight | The protein has a predicted MW of 35.2 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1 EU per μg by the LAL method. |
Purity | >95% as determined by Tris-Bis PAGE. |
Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Please dilute to the desired concentration according to the concentration of the solution shown on the product label. |
Storage | Valid for 12 months from date of receipt when stored at -80℃. |
Notes | Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles. |