Human 4-1BB/CD137 Protein
CAT#: ICP-A003
Inquiry
Overview
Specification
| Species
|
Human |
| Tag
|
C-His |
| Expression Systems
|
Expi293 |
| Keywords
|
Human; C-His; Expi293 |
| Synonyms
|
CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA |
| Background
|
4-1BB, also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes, and cells of blood vessel walls at sites of inflammation. |
| Source
|
Recombinant Human 4-1BB/TNFRSF9 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Leu24-Gln186. |
| Molecular Weight
|
The protein has a predicted MW of 18.1 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
| Endotoxin
|
Less than 1 EU per μg by the LAL method. |
| Purity
|
>95% as determined by Tris-Bis PAGE.
>95% as determined by HPLC. |
| Formulation
|
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
| Reconstitution
|
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage
|
-20 to -80℃ for 12 months as supplied from the date of receipt.
-20 to -80℃ for 3-6 months in an unopened state after reconstitution.
2-8℃ for 2-7 days after reconstitution. |
| Notes
|
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Related Products
