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Human TIGIT Protein

Human TIGIT Protein

CAT#: ICP-A022

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Overview Specification

Species	Human
Tag	C-His
Expression Systems	Expi293
Keywords	Human; C-His; Expi293

Synonyms	TIGIT; VSIG9; VSTM3; WUCAM
Background	TIGIT, also called Vstm3, Vsig9, and WUCAM is a transmembrane protein in the CD28 family of the Ig superfamily proteins. IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and are up-regulated following activation of these cells.
Source	Recombinant Human TIGIT Protein is expressed from Expi293 with His tag at the C-terminal. It contains Met22-Pro141.
Molecular Weight	The protein has a predicted MW of 14 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
Endotoxin	Less than 1 EU per μg by the LAL method.
Purity	>95% as determined by Tris-Bis PAGE. >95% as determined by HPLC.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage	-20 to -80℃ for 12 months as supplied from the date of receipt. -20 to -80℃ for 3-6 months in an unopened state after reconstitution. 2-8℃ for 2-7 days after reconstitution.
Notes	Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.

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