NF-M Polyclonal Antibody

CAT#: NEM-K007

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Overview Specification

Target	NF-M
Cell Type	Dopaminergic, glutamatergic, GABAergic neurons
Host	Rabbit
Isotype	IgG
Applications	WB, IHC, IF, ELISA
Reactivity	Human, mouse, rat, canine
Conjugate	Unconjugated
Keywords	Dopaminergic, glutamatergic, GABAergic neurons; Rabbit; IgG; WB, IHC, IF, ELISA

Product Information	The immunogen of NF-M Fusion Protein expressed in E. coli.
Background Information	NEFM, also named as NEF3 and NFM, belongs to the intermediate filament family. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE:NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody recognizes endogenous NF-M protein.
Synonyms	160 kDa neurofilament protein, NEF3, NEFM, neurofilament, Neurofilament 3, NF, NF M, NFM, NF-M
Full Name	Neurofilament, medium polypeptide
Tested Reactivity	Human, rat, mouse
Type	Antibody
Class	Polyclonal
Immunogen	NF-M fusion protein
Calculated Molecular Weight	102 kDa
Observed Molecular Weight	140 kDa
GenBank Accession Number	BC002421
Gene ID	4741
Gene Symbol	NEFM
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Mouse brain tissue, rat brain tissue
Positive IHC Detected	Mouse cerebellum tissue, human brain tissue, human colon tissue, mouse brain tissue
Positive IF Detected	Mouse brain tissue

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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