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PAX6 Monoclonal Antibody

PAX6 Monoclonal Antibody

CAT#: NEM-K010

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Overview Specification

Target	PAX6
Cell Type	Dopaminergic neurons
Host	Mouse
Isotype	IgG1
Applications	WB, IHC, IF, ELISA
Reactivity	Human, mouse, rat
Conjugate	Unconjugated
Keywords	Dopaminergic neurons; Mouse; IgG1; WB, IHC, IF, ELISA

Product Information	It targets PAX6 in WB, IHC, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.
Background Information	PAX6, a paired domain and homeodomain-containing transcription factor. Interaction with TRIM11 leads to ubiquitination of PAX6 and its proteasomal degradation. PAX6 is one of the earliest genes expressed in the eye field and considered a master control gene for retinal and eye development. PAX6 also regulates the development of the olfactory, central nervous systems, pituitary, and pancreas. PAX6 mutations can cause complex ocular disorders such as aniridia and Peter's anomaly.
Synonyms	AN, AN2, Aniridia type II protein, D11S812E, MGDA, Oculorhombin, paired box 6, Paired box protein Pax 6, PAX6, WAGR
Full Name	Paired box 6
Tested Reactivity	Human, mouse, rat
Type	Antibody
Class	Monoclonal
Immunogen	PAX6 fusion protein
Calculated Molecular Weight	47 kDa
Observed Molecular Weight	47 kDa
GenBank Accession Number	BC011953
Gene ID	5080
Gene Symbol	PAX6
Form	Liquid
Purification Method	Protein A purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Rat retina tissue, JAR cells, hTERT-RPE1 cells, HeLa cells, K-562 cells, Neuro-2a cells
Positive IHC Detected	Mouse eye tissue, mouse brain tissue, rat brain tissue

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