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PSD95-Specific,DLG4 Polyclonal Antibody

PSD95-Specific,DLG4 Polyclonal Antibody

CAT#: NEM-K011

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Overview Specification

Target	PSD-95
Cell Type	Dopaminergic, glutamatergic, GABAergic neurons
Host	Rabbit
Isotype	IgG
Applications	WB, IHC, IF, FC, ELISA
Reactivity	Human, mouse, rat, hamster
Conjugate	Unconjugated
Keywords	Dopaminergic, glutamatergic, GABAergic neurons; Rabbit; IgG; WB, IHC, IF, FC, ELISA

Product Information	It targets PSD95-Specific,DLG4 in WB, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.
Background Information	Background InformationPSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene. PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation. Observed MW of PSD95 is 90-95 kDa due to phosphorylation (PMID: 20682303).
Synonyms	Disks large homolog 4, DLG4, PSD 95, PSD95, PSD95-Specific,DLG4, SAP 90, SAP90, Synapse associated protein 90
Full Name	Discs, large homolog 4 (Drosophila)
Tested Reactivity	Human, mouse, rat
Type	Antibody
Class	Polyclonal
Immunogen	Peptide
Calculated Molecular Weight	85 kDa
Observed Molecular Weight	90-95 kDa
GenBank Accession Number	NM_001365
Gene ID	1742
Gene Symbol	DLG4
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Mouse brain tissue, HeLa cells, rat brain tissue
Positive IHC Detected	Mouse brain tissue

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