SMARCA4/BRG1 Polyclonal Antibody

CAT#: NSC-P021

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Overview Specification

Target	SMARCA4/BRG1
Cell Type	NSCs
Host	Rabbit
Isotype	IgG
Applications	WB, RIP, IP, IHC, IF, CoIP, ChIP, ELISA
Reactivity	Human, mouse, rat, zebrafish
Conjugate	Unconjugated
Keywords	NSCs; Rabbit; IgG; WB, RIP, IP, IHC, IF, CoIP, ChIP, ELISA

Product Information	The immunogen of SMARCA4/BRG1 Fusion Protein expressed in E. coli.
Background Information	SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Synonyms	ATP dependent helicase SMARCA4, BAF190, BAF190A, BRG1, BRG1 associated factor 190A, hSNF2b, Protein brahma homolog 1, Protein BRG 1, SMARCA4, SMARCA4/BRG1, SNF2, SNF2 BETA, SNF2B, SNF2L4, SNF2LB, SWI2, Transcription activator BRG1
Full Name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Tested Reactivity	Human, mouse, rat
Cited Reactivity	Human, mouse, bovine, zebrafish
Class	Polyclonal
Type	Antibody
Immunogen	SMARCA4/BRG1 fusion protein
Calculated Molecular Weight	1647 aa, 185 kDa
Observed Molecular Weight	185 kDa
Gene ID	6597
GenBank Accession Number	BC150298
Gene Symbol	SMARCA4
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	HepG2 cells, mouse brain tissue, rat brain tissue, human placenta tissue, HeLa cells
Positive IP Detected	HeLa cells
Positive IHC Detected	Human colon cancer tissue, human lung cancer tissue, mouse kidney tissue, human breast cancer tissue, human gliomas tissue
Positive IF Detected	HepG2 cells, HEK-293 cells, Hela cells

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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