Synaptophysin Polyclonal Antibody

CAT#: NEM-K012

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Overview Specification

Target	Synaptophysin
Cell Type	Dopaminergic, glutamatergic, GABAergic, motor neurons
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, ELISA
Reactivity	Human, mouse, rat, hamster
Conjugate	Unconjugated
Keywords	Dopaminergic, glutamatergic, GABAergic, motor neurons; Rabbit; IgG; WB, IP, IHC, IF, ELISA

Product Information	It targets Synaptophysin in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Background Information	Synaptophysin (SYP, also known as major synaptic vesicle protein p38) is a 38-kDa integral membrane glycoprotein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass. Synaptophysin is present in neuroendocrine cells and neurons that participate in synaptic transmission. Synaptophysin is a useful marker for identification of neuroendocrine cells and neoplasms. (PMID: 3010302; 21658579)
Synonyms	SYN, synaptophysin, SYP
Full Name	Synaptophysin
Tested Reactivity	Human, mouse, rat
Type	Antibody
Class	Polyclonal
Immunogen	Synaptophysin fusion protein
Calculated Molecular Weight	313 aa, 34 kDa
Observed Molecular Weight	38-40 kDa
GenBank Accession Number	BC064550
Gene ID	6855
Gene Symbol	SYP
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Mouse brain tissue, human brain tissue, mouse cerebellum tissue, rat brain tissue
Positive IP Detected	Mouse brain tissue
Positive IHC Detected	Mouse brain tissue, ganglioma tissue, human brain tissue, human pituitary adenoma tissue, human pancreas tissue, neuroblastoma tissue, mouse pancreas tissue
Positive IF Detected	Mouse pancreas tissue, PC-12 cells, human lung cancer tissue, mouse brain tissue, human gliomas tissue

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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