TH Polyclonal Antibody

CAT#: NEM-K013

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Overview Specification

Target	TH
Cell Type	Dopaminergic neurons
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, ELISA
Reactivity	Human, mouse, rat, canine, gerbil, zebrafish
Conjugate	Unconjugated
Keywords	Dopaminergic neurons; Rabbit; IgG; WB, IP, IHC, IF, ELISA

Product Information	The immunogen of is TH Fusion Protein expressed in E. coli.
Background Information	TH(Tyrosine 3-monooxygenase) converts L-tyrosine to L-3,4-dihydroxyphenylalanine, the essential and rate-limiting step to formation of dopamine and other catecholamines. TH plays an important role in the physiology of adrenergic neurons and can be used as a marker for dopaminergic and noradrenergic neurons. This protein has 6 isoforms produced by alternative splicing with the MW from 44 kDa to 58 kDa.
Synonyms	TH, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, tyrosine hydroxylase
Full Name	Tyrosine hydroxylase
Tested Reactivity	Human, mouse, rat
Type	Antibody
Class	Polyclonal
Immunogen	TH fusion protein
Calculated Molecular Weight	528 aa, 59 kDa
Observed Molecular Weight	50-55 kDa
GenBank Accession Number	BC104967
Gene ID	7054
Gene Symbol	TH
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Positive WB Detected	Mouse brain tissue, rat brain tissue
Positive IP Detected	Mouse brain tissue
Positive IHC Detected	Mouse brain tissue, mouse heart tissue, rat brain tissue
Positive IF Detected	Mouse brain tissue, SH-SY5Y cells

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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