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Omics Analysis Services for Prostate Cancer
Omics is the science of large-scale analysis of complex systems of living organisms in the fields of biology and medicine. Multivariate signatures are expected to play a role in prostate cancer detection, screening, patient classification, assessment of treatment response, and biomarker identification. With a deep understanding of the unique challenges associated with prostate diseases, Alfa Cytology provides multiple omics analysis services for prostate cancer.
Introduction to Omics Analysis
Comprehensive and quantitative analysis of molecular classes in biological samples is known as omics, and in recent years large-scale omics studies targeting different prostate cancer stages have been conducted. Prostate tumors are the second most common type of cancer and a common cause of cancer deaths in men worldwide. It is a very heterogeneous disease, so assessing inter- and intra-tumor variation is critical to accurately understand disease progression and plasticity and to develop personalized therapies.
Fig. 1 Multi-omic strategy
in Prostate cancer study. (Gholami N., et al. 2022)
Types of Omics Analysis
Omics analysis usually involves a comprehensive study of biological molecules (e.g., genes, proteins, metabolites, etc.) to understand their roles and interactions in an organism. The following are some common areas of omics.
DNA-seq
DNA sequencing (DNA-seq) involves the sequencing of DNA molecules to identify specific sequence variations in the genome, such as single nucleotide polymorphisms (SNPs), insertions and deletions.
RNA-seq
RNA sequencing (RNA-seq) is used to study the transcriptome, the collection of all RNA molecules. It enables precise definition of gene structure and accurate measurement of gene expression levels.
ChIP-seq
Chromatin Immunoprecipitation sequencing (ChIP-seq) is used to analyze protein-DNA interactions, discriminate and quantify specific DNA sequences that bind proteins or have epigenetic modifications present.
Cistromic
Cistromic refers to the genome-wide targeting of a trans regulatory factor - a set of cis acting elements. It's used to discover the cis and trans-groups of transcription factors and other chromatin-associated factors.
ATAC-seq
Assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) obtains information on all open chromatin regions on the whole genome at a specific spatio-temporal level.
Metabonomics
Metabonomics analysis involves the qualitative and quantitative analysis of small molecule metabolites in biological samples to understand metabolic pathways and metabolic networks in organisms.
Multi-omics Joint Analysis
Multi-omics Joint analysis combines data from different groups to provide a more comprehensive view of biological systems, helping to reveal interactions at different molecular levels.
Single-Cell Omics
Single-cell omics profiling is a genomic analysis of gene expression, epigenetic modification, and protein expression at the single-cell level to reveal the heterogeneity of cell populations.
Spatial Omics
Spatial omics represents a revolutionary tool in biomedical research, combining tissue sectioning techniques with omics analysis to resolve the spatial distribution of molecular changes at the tissue level.
Our Services
Based on the multi-omics analysis platform, we can gain a deeper understanding of the molecular pathways involved in the progression of prostate cancer, as well as response and resistance to treatment, thus further facilitating the early diagnosis and development of therapeutic approaches for prostate cancer. At Alfa Cytology, we provide more effective, and more personalized multiple omics analysis services for prostate cancer.
- DNA-seq Services
- RNA-seq Services
- ChIP-seq Services
- Cistromic Services
- ATAC-seq Services
- Metabonomic Profiling
- Multi-omics Joint Analysis
- Single-Cell Omics Profiling
- Spatial Omics Profiling
- And More
Workflow for Omics Analysis
Cell Suspension
Library Construction
Sequencing
Data Analysis
Visualization
If you are looking to omics analysis for prostate cancer, our expert team provide comprehensive support. By partnering with us, you'll receive personalized consulting services and efficient project advancement. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.
Reference
- Gholami N, et al. Prostate cancer in omics era. Cancer Cell Int. 2022, 22(1): 274.
For research use only.