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Prostate Cancer Cell Line Customization Service
Stable cell lines play a crucial role in prostate cancer research and development of new therapies. Alfa Cytology offers a one-stop prostate cancer cell line development service, providing you with customized stable cell lines to ensure that your research projects can move forward with efficiency and precision.
Introduction to Prostate Cancer Cell Line
Prostate cancer cell lines are cell populations with certain biological characteristics extracted from prostate tissues and cultured and proliferated in vitro. These cell lines can be used to study the pathogenesis of prostate cancer, drug screening, gene function studies, and the development of new therapeutic strategies.
Types of Prostate Cancer Cell Line
In clinical practice, prostate cancer is closely associated with androgen receptor (AR) expression. Therefore, commonly used human prostate cancer cell lines are usually categorized into two main groups based on AR expression: androgen receptor-positive cell lines and androgen receptor-negative cell lines.
| Name | AR | Tumor Formation | Application |
| LNCaP | + | LNCaP cells can form tumors in nude mice. | Growth and metastasis studies, Androgen receptor function studies. |
| 22RV1 | + | 22RV1 cells are capable of forming PSA-positive tumors in nude mice. | Growth and metastasis studies, Androgen receptor function studies. |
| VCaP | + | VCaP cells are capable of forming tumors in both nude mice and SCID mice. | Growth and metastasis studies, Androgen receptor function studies. |
| PC3 | - | PC3 cells were grown in agar and produced tumors in nude mice. | Growth and metastasis studies |
| DU145 | - | DU145 cells can form adenocarcinoma (grade II) consistent with prostatic primary in nude mice. | Growth and metastasis studies |
Our Services
Alfa Cytology specializes in providing comprehensive cell line development services for prostate cancer research, including the construction and optimization of customized stable cell lines. Our dedicated team of professionals is committed to meeting your specific needs for cell models in drug discovery, compound screening and gene therapy research, ensuring that your research program is supported by high-quality, reliable cell lines.
Primary Cell Line
Different primary prostate cancer cell lines are provided by directly isolating and culturing cells from tumor tissue of prostate cancer patients.
iPS Cells
Provide various types of reprogrammed pluripotent stem cells that can be differentiated into prostate cancer cells through iPSC editing system.
CRISPR Knockout Cell Lines
Provides precise disruption of specific genes of interest in prostate cancer cell lines using proven CRISPR-Cas9 gene editing technology.
Knockdown Cell Lines
By using RNA interference (RNAi) technology, we achieved an effective reduction in the expression of specific target genes in prostate cancer cell lines.
Knockin Cell Lines
Knockdown Cell Line Service enables precise integration of exogenous DNA sequences into prostate cancer cell lines.
Overexpression Cell Lines
Overexpression Cell Line Service provides the generation of prostate cancer cell lines with controlled and stable overexpression of target genes.
With extensive experience and advanced platforms, we offer you the best solution for customized cell lines for prostate cancer. Our company is a world leader in prostate cancer therapy development. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.
For research use only.